The best way to beat Hyperius is to use the Infinity Pistol and the bee shield with electrical immunity. First kill all of his minions and make sure you distance your self from Hyperius while doing this. & if he gets close to you, have someonee to use either their Deception skill or their Death Trap to distract him. After you kill his minions, have everyone unload their infinity pistol on him. This is probably the easiest way to kill him.