Much like the Achievements for Code Veronica X HD, the Achievements for Resident Evil 4 HD mostly revolve around story progression, save for two we're sure are going to give you a tough time.The "What are they worth?" and "The S stands for stylish!!" Achievements can be unlocked only after you acquire all bottlecaps and costumes, respectively.
Succeeding in that doubly tough endeavor will get you 250 Gamerscore (out of the possible 1,000). And if there's something more important than imaginary points tied to one platform, we don't wanna hear about it.